FMCSA 49 CFR 396.17 requires that every commercial motor vehicle — including each component of a combination such as a trailer or converter dolly — be inspected at least once every twelve months. The inspection must cover, at minimum, all the components listed in Appendix A to Part 396: brake system, coupling devices, exhaust system, fuel system, lighting, safe loading, steering, suspension, frame, tires, wheels and rims, windshield glazing, and wipers.
Crucially, the person performing the inspection must be a qualified inspector under 49 CFR 396.19 — meaning they have the knowledge and training to identify defects and have passed an FMCSA-recognized program, or hold equivalent training and experience. The inspector's qualification must be documented and retained by the carrier; this is a separate requirement from the brake-inspector qualification in 396.25.
Proof of the annual inspection travels with the vehicle. The carrier must keep a copy of the inspection report, and the vehicle must display a periodic-inspection decal or carry the report. A vehicle that passes a roadside inspection under a CVSA program can have that inspection accepted in lieu of the annual periodic inspection, which is why many fleets time the annual around a clean roadside or self-inspection.
The DOT annual is the heaviest of the FMCSA inspection cadences — distinct from the daily pre-trip (396.13) and end-of-day DVIR (396.11). Where the daily checks are about catching defects that emerge in service, the annual is a deep, component-level verification that the whole vehicle still meets the minimum Appendix A standards.